Find the plateau. Then fix it.

Panel

Core Metabolic Panel

Price

$169

Shipping

Next Day

01

HOMA-IR above 2.5 with a fat loss plateau is the clinical signal

Most fat loss plateaus are attributed to dietary adherence. MOTS-C addresses a different mechanism entirely — cellular energy efficiency. When HOMA-IR confirms insulin resistance is present despite protocol adherence, MOTS-C has a documented physiological target.

02

Triglycerides are the most sensitive marker of insulin resistance

Elevated triglycerides above 150 mg/dL — especially alongside low HDL — are a classic pattern of cellular insulin resistance. MOTS-C activates AMPK signalling, which directly addresses this pathway. The baseline documents the starting point; the 90-day retest shows the response.

03

Rule out thyroid before attributing the plateau to metabolism

Hypothyroidism and insulin resistance produce nearly identical fat loss plateau presentations. TSH eliminates the thyroid explanation — so when it comes back normal alongside elevated HOMA-IR, the metabolic pathway is confirmed.

What's Included

Core Metabolic Panel — $169

Order Today

Core Metabolic Panel

$169

On GLP-1 and hitting a plateau? HOMA-IR and triglycerides identify whether insulin resistance is blunting your GLP-1 response — and whether MOTS-C is the missing piece.

01

Order online

Choose your panel. Enter your details and check out in under 2 minutes.

02

Test at home

Your your at-home testing kit arrives next day. Painless upper-arm collection — no lab, no venipuncture.

03

Get results + protocol

Results in 3–5 business days. Your physician reviews and schedules your interpretation call within 48 hours.

Also consider

Full Metabolic Package — $399

The $399 package includes HOMA-IR, biological age, gut microbiome, and physician interpretation — the complete metabolic picture before designing your protocol.

When will MOTS-C be available to prescribe?

MOTS-C has cleared the major FDA regulatory hurdles. Dispensing is expected around October 2026. Testing now establishes your metabolic baseline so your physician can prescribe and track response from day one.

Do I need to be fasting for this panel?

Yes — an 8-hour overnight fast is required for accurate fasting glucose, triglycerides, and lipid markers. Water and medications are fine.

What HOMA-IR level indicates MOTS-C?

HOMA-IR above 2.5 indicates moderate insulin resistance. Above 3.5 indicates significant resistance. Both thresholds suggest the cellular energy dysfunction pathway that MOTS-C addresses via AMPK activation. Your physician interprets your value in context of your full panel.

Is this panel HSA/FSA eligible?

Yes. Physician-ordered diagnostic testing is HSA and FSA eligible. At a 32% bracket, the effective cost is approximately $115.