Laboratory data can be one part of a broader clinical evaluation. History, current medicines, symptoms, examination, and treatment-specific guidance may also matter. A catalog blood panel cannot replace that evaluation or forecast an individual result.
Here are eight testing categories sometimes discussed in metabolic care and the limits of what each result can show. Your own licensed clinician decides what is appropriate.
These categories are an educational testing framework, not a list of results from one WellSpry kit. WellSpry's widest at-home panel returns 18 catalog-listed markers. Fasting insulin, free testosterone, full thyroid testing, gut microbiome analysis, cortisol, and any other value outside that list require separate outside testing. Neither the panel nor this framework establishes treatment eligibility, safety, or efficacy.
HbA1c + Fasting Insulin
HbA1c and fasting insulin describe different aspects of glucose regulation. Whether either test is appropriate, and how it should be interpreted, depends on the laboratory method and individual clinical context. Fasting insulin is not returned by a WellSpry at-home panel.
ApoB
ApoB estimates the number of atherogenic lipoprotein particles and can provide cardiovascular context alongside other findings. It does not by itself select a medication, establish candidacy, or predict an individual treatment result.
hs-CRP
hs-CRP is a nonspecific inflammatory marker whose interpretation can be affected by infection, injury, chronic conditions, and laboratory context. It does not predict GLP-1 response or establish a supplement or treatment plan.
Total + Free Testosterone
Testosterone results require sex-specific laboratory ranges and individual clinical context. They do not determine muscle-loss risk, GLP-1 eligibility, or whether a hormone, peptide, or other treatment is appropriate. Free testosterone is not returned by a WellSpry at-home panel.
Thyroid Panel (TSH, Free T3, T4)
Thyroid testing may be appropriate when history or symptoms support it. Results require interpretation with laboratory ranges and clinical findings; they do not establish medication eligibility, safety, or expected weight change. Free T3 and T4 require separate outside testing if an independent clinician needs them.
Vitamin D (25-OH)
Vitamin D can provide nutrient-status context, but a result does not predict GLP-1 side effects or prove that supplementation will change a treatment outcome. Supplement decisions should account for the result, medical history, and the patient's own clinician's advice.
Gut Microbiome (gut microbiome)
Microbiome research is evolving, and consumer stool scores are not validated as a universal predictor of GLP-1 symptoms or response. Stool microbiome analysis is not included in a WellSpry at-home blood panel and should be ordered only when an independent clinician finds it appropriate.
Cortisol AM
Cortisol varies with timing, sleep, stress, medicines, illness, and collection conditions. An isolated result does not predict GLP-1 response or determine an exercise, supplement, or treatment plan. Cortisol is not returned by a WellSpry at-home panel.
The Comprehensive GLP-1 Test returns only its catalog-listed markers; it does not include gut microbiome analysis or every category discussed above, and it is not treatment clearance. Bring any required outside testing to your own licensed clinician. Choose Health handles account activation, consent, lab processing, clinician review, and secure portal delivery.
Get My Testing Kit — $279 →Frequently Asked Questions
What blood tests should I get before starting GLP-1?
There is no universal laboratory list for every patient. An independent licensed clinician can choose testing based on medical history, symptoms, the medicine being considered, and current guidance. This educational framework is not the composition of a WellSpry kit, and a WellSpry panel does not establish treatment eligibility or safety.
Does insurance cover blood tests before GLP-1?
Coverage and HSA/FSA reimbursement depend on your plan and the applicable expense rules. The Comprehensive GLP-1 Test is a one-time $279 purchase for 18 catalog-listed markers; confirm eligibility with your insurer or plan administrator before purchase. Recommended values outside that catalog require separate testing.
What is the most important blood test before starting Wegovy or Zepbound?
No single test is most important for every patient, and laboratory results are only one part of a clinical evaluation. The patient's own licensed clinician determines which history, examination, and testing are appropriate. Fasting insulin is not returned by a WellSpry at-home panel and requires separate outside testing if that clinician needs it.